Correlation between coping-adaptation level and self-consistency among molecular targeted therapy related rash patients with nonsmall-cell lung cancer

Abstract

Objective To explore the correlation between coping-adaptation level and self-consistency among molecular targeted therapy related rash patients with nonsmall-cell lung cancer (NSCLC) and to analyze the influencing factors of the coping-adaptation level. Methods From June 2014 to June 2017, we selected 108 rash and NSCLC patients with molecular targeted therapy in the Third People's Hospital of Zhengzhou. The coping-adaptation and self-consistency were evaluated with the Chinese Version of Coping-adaptation Processing Scale: Short Form (CV-CAPS: SF) and Self Consistency and Congruence Scale (SCCS) . Data was analyzed statistically with the SPSS 22.0. Results Among 108 molecular targeted therapy related rash patients with NSCLC, the scores of coping-adaptation as well as self-consistency were (38.94±6.14) and (130.00±15.50) . Pearson correlation analysis showed that coping-adaptation had a positive correlation with the self-flexibility (P<0.01) , and had negative correlations with disharmony between self and experience as well as self-stiffness (P<0.01) . There were statistical differences in the scores of coping-adaptation among molecular targeted therapy related rash and NSCLC patients with different sexes, ages, educational levels, vocation, personal monthly income, reimbursement rate of medical insurance and whether to live with their children (P<0.01) . Multiple linear regression showed the influencing factors of coping-adaptation included sexes, ages, educational levels, personal monthly income (P<0.01) . Conclusions Coping-adaptation and self-consistency of molecular targeted therapy related rash patients with NSCLC need improvement with correlations between them. Medical staff should take positive and effective measures to improve cognition of patients on treatment, so as to enhance their coping-adaptation levels and self-consistency. Key words: Molecular targeted therapy; Exanthema; Coping-adaptation; Self-consistency