Abstract
Purpose: Knee osteoarthritis is a common chronic joint disease affecting the whole joint. There is some evidence that increased quadriceps strength and muscle cross-sectional area (CSA) may help alleviate symptoms and slow disease progression, but the data is inconclusive. The aim of the study was to examine (1) the association between vastus medialis CSA and tibial cartilage volume cross-sectionally and longitudinally over 2 years, and (2) the association between vastus medialis CSA and knee pain and function cross-sectionally and longitudinally over 2 years, in individuals with symptomatic knee osteoarthritis.
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