Abstract

In the report "Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation" by M. E. Gurney et al. (17 June 1994, p. 1772)(1), a systematic, 10-fold error was made in calculating the dilutions of brain extract used for determinations of total brain superoxide dismutase (SOD) activity shown in column 6 of table 1 (p. 1774). Each value reported should have been reduced by that factor, for example, the total SOD activity reported for the G1 line should have been 4.26 ± 0.2 SOD (U)/total protein (μg), not 42.6 ± 2.1 U/μg, and so forth.

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