Abstract
[This corrects the article DOI: 10.18632/oncotarget.15577.].
Highlights
Ground-glass opacity (GGO) is defined as an area of hazy increased attenuation that does not obscure underlying bronchial structures or vascular markings on high-resolution computed tomography (HRCT) [1]
Significant differences were found in the diameter of GGN (DGGN), Dsolid, and consolidation/ tumor ratio (CTR) between the two groups
DGGN and Dsolid were respectively correlated with both SUVmax and CTR, whereas cystic appearance was reverse correlated with both SUVmax and CTR
Summary
Ground-glass opacity (GGO) is defined as an area of hazy increased attenuation that does not obscure underlying bronchial structures or vascular markings on high-resolution computed tomography (HRCT) [1]. Patients with stage IA lung adenocarcinoma (i.e., peripheral lung cancers ≤ 3 cm in diameter without nodal and distant metastasis), usually present as a solitary ground-glass opacity nodule (GGN) on HRCT [2,3,4,5], and have a 5-year disease-free survival rate approaching 88% [6]. A percentage of 0.5 or less of the solid component of a GGN can identify early lung adenocarcinoma with clinical T1bN0M0 patients [13] and can be a useful independent preoperative prognostic indicator [23]. Among various strategies over morphologic evaluation, contrast-enhanced and dynamic MDCT have been applied to assess malignant GGNs with limited additional information [12]. Perfusion MDCT shows us promising for lung cancer [24], the increased radiation dose restricts its clinical application
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