Abstract
Correction: Effects of Gender and Age on Development of Concurrent Extrapulmonary Tuberculosis in Patients with Pulmonary Tuberculosis: A Population Based Study
Highlights
Tuberculosis (TB) is a major threat to public health worldwide and is currently the second leading cause of death from infectious disease, after HIV/AIDS [1]
M. tuberculosis usually invades a human host via the respiratory tract, and about 80% of TB patients are diagnosed with pulmonary TB (PTB) [3]
Our results indicated that gender, HIV co-infection, and cough $3 weeks were the three independent factors influencing extrapulmonary TB (EPTB): women were more likely than men to have concurrent EPTB; PTB patients with HIV co-infection were more likely to have concurrent EPTB; and those with cough $3 weeks were less likely to have concurrent EPTB
Summary
Tuberculosis (TB) is a major threat to public health worldwide and is currently the second leading cause of death from infectious disease, after HIV/AIDS [1]. 5% to 10% of M. tuberculosis–infected individuals develop TB [3], and most adult-onset cases result from reactivation of dormant infections [4], suggesting that interactions between the host and M. tuberculosis bacilli clearly affect the development of TB [5]. M. tuberculosis usually invades a human host via the respiratory tract, and about 80% of TB patients are diagnosed with pulmonary TB (PTB) [3]. Some PTB patients present with concurrent extrapulmonary TB (EPTB), a more serious condition. This suggests that the immune systems of PTB patients who develop concurrent EPTB cannot prevent M. tuberculosis bacilli from extending beyond the lung parenchyma. Analysis of the epidemiological characteristics of TB patients with different severities of disease may advance our understanding of the causes of EPTB [4]
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