Abstract

[This corrects the article DOI: 10.1371/journal.pone.0149100.].

Highlights

  • Parameter AUC % extrapolated AUC (0 to infinity) AUC (0 to Cn) Cmax Ke T 1⁄2 Ke MRT Tmax Tissue Penetration

  • AUC, Area-under-the-curve, from zero to the last time point (Cn), and from 0 to infinity; AUC % extrapolated is the percent extrapolated to infinity

  • Peak (maximum) concentration; Tmax, time to peak concentration; Penetration factor, ratio of AUC values of tissue site: plasma; Ke, elimination (terminal) rate, and associated half-life, T1⁄2; MRT, mean residence time

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Summary

Introduction

Parameter AUC % extrapolated AUC (0 to infinity) AUC (0 to Cn) Cmax Ke T 1⁄2 Ke MRT Tmax Tissue Penetration.

Results
Conclusion
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