Abstract

Rare infections, known as signal infections might be pathognomonic for patients with diabetes mellitus. A 55-year-old man without a significant medical history was admitted to our hospital with polyuria, polydipsia, dysuria, fever, chills and weight loss for the last month. A laboratory investigation showed leukocytosis and, elevated levels of C-reactive protein, sedimentation rate, blood glucose, and HbA1c. The patient was hospitalized in the internal medicine service and started intensive insulin therapy with intravenous saline infusion. The patient's fever and chills were not improved despite ceftriaxone treatment for three days. Ceftriaxone-resistant, imipenem-sensitive E. coli was grown in the blood cultures, so ceftriaxone was stopped and imipenem plus cilastatin combination was started. Detailed physical examination of the patient for fever etiology showed severe swelling in the perineal region. Superficial and scrotal ultrasonography and then pelvic magnetic resonance imaging revealed corpus spongiosum abscess. The perineal region was punctured and numerous Gram-negative bacilli and polymorphonuclear leukocytes were seen in the gram stain. Drainage catheter was inserted into the corpus spongiosum. Blood sugar levels were regulated and the patient was discharged after the antibiotic treatment was completed. As in our case, signal infections should be kept in mind especially in patients admitted with new onset of diabetes mellitus and persistent fever. A detailed physical examination should be performed in these patients and atypical areas like perineum should be carefully examined.

Highlights

  • Diabetes mellitus (DM) is characterized by the deficiency of insulin secretion or action [1]

  • Known as signal infections might be pathognomonic for patients with diabetes mellitus

  • Signal infections should be kept in mind especially in patients admitted with new onset of diabetes mellitus and persistent fever

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Summary

INTRODUCTION

Diabetes mellitus (DM) is characterized by the deficiency of insulin secretion or action [1]. Signal infections are rare and severe infections that are not self-limiting and likely to be diagnosed regardless of differences in physician behavior or previous diabetes diagnosis. They are often pathognomonic of a patient with diabetes mellitus [4]. We report a case of corpus spongiosum abscess as a rare infection and new onset of diabetes mellitus in a patient presented with fever, chills and weight loss. Detailed physical examination of the patient for fever etiology showed severe swelling with palpation in the perineal region. Superficial and scrotal ultrasonography of the patient revealed an irregular hypoechoicheterogeneous collection area consistent with abscess, approximately 50x30 mm in size, in the perineal region of the corpus spongiosum.

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