Corpus callosum infarction： clinical and imaging features

Abstract

Objective To investigate the clinical and imaging features in patients with corpus callosum infarction. Methods The patients with corpus callosum infarction confirmed by MRI were collected retrospectively. Their clinical manifestations and imaging data were analyzed. Results The corpus callosum infarction accounted for 1.04% of all patients with cerebral infarction. Its major risk factors were hypertension, coronary heart disease, and diabetes. Its typical clinical manifestations included ideomotor apraxia （42. 9% ）, frontal gait （28. 6%） and alien hand syndrome （14. 3%） accompanied with limb paralysis, disturbance of consciousness, cognitive impairment and other symptoms. MRI detected 8 corpus callosum lesions. Most were involved in the body of corpus callosum （62. 5% ）, followed by splenium （25.0%） and genu （1/8, 12. 5% ）. The frontal lobe （57. 1% ）, basal antglia （42. 9% ） and occipital lobe （42. 9% ） were frequently involved. Diffusion tensor imaging revealed that the fiber connections of the body and genu of corpus callosum were broken in one case. Angiography showed that 6 patients had vascular stenosis or occlusion, and the most common was vertebral artery stenosis （66. 7% ）, followed by anterior cerebral artery （50. 0% ）, and common carotid artery, internal carotid artery and middle cerebral artery stenoses were rare （all 33.3% ）. Conclusions The incidence of corpus callosum infarction is low. Atherosclerosis is the pathogenic key. Its clinical manifestations are diverse, and they are associated with the sites of infarction. Key words: Cerebral Infarction; Corpus Callosum; Magnetic Resonance Imaging