Clinical and hnaging analysis of corpus callosum infarction

Abstract

Objective To investigate the clinical and imaging characteristics in patients with corpus callosum infarction. Methods The clinical data of 416 patients meeting the diagnosis of cerebral infarction were collected, in which, 8 patients were confirmed as corpus caUosum infarction by MRI. Results Corpus callosum infarction accounted for 1.9% of all patients with cerebral infarction. CT scan did not show the corpus callosum infarctions in 7 patients, The non- enhanced MRI revealed the lesions. The enhanced MRI revealed the lesion in another patient. The infarction foci were not only involved in the corpus callosum （knee, body or splenium）, but also complicated with frontal lobe, occipital lobe and thalamus infarctions. The clinical manifestations of the corpus callosum infarction were different due to the specific lesion sites. The simple infarction in the body of the corpus callosum mainly presented as contralateral paraparesis, ataxia, and left limb apraxia; the infarction in the knee of the corpus callosum mainly presented as lower limb paralysis or contralateral paraparesis; the infarction in the splenium of the corpus callosttm presented as limb paralysis and dizziness; the lacunar infarct in the corpus callosttrn had no obvious clinical manifestations. The patients who complicated with frontal lobe and thalamus infarction had behavioral and psychological symptoms, including mental retardation, language abnormalities, and incontinence. Conclusions Corpus callosum infarction is not common. MRI is the basis of diagnosis. The clinical manifestation is lack of specificity, and it is associated with the location of corpus callosum infarction and whether it complicates with the infarction on other part. Key words: Cerebral Infarction; Corpus Callosum; Tomography, X-Ray Computed; Magnetic Resonance Imaging