Abstract

A woman in the United States is more likely to die from coronary heart disease than from any other health problem. Yet, despite the fact that coronary heart disease is the leading cause of death in U.S. women, responsible for almost 1/4 million fatalities annually, virtually all the information used daily by physicians related to the prevention, clinical recognition, management, and prognosis of coronary heart disease is derived from studies conducted predominantly or exclusively in middle-aged men [1–3]. This manuscript reviews the evolution of our knowledge about coronary heart disease in women, in particular addressing how much of the traditional male model of coronary heart disease is applicable to coronary illness in older women.

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