Corelation of malnutrition inflammation complex syndrome and sarcopenia

Abstract

Objective To investigate the relationship of malnutrition inflammation complex syndrome(MICS) in maintenance hemodialysis(MHD) patients with sarcopenia. Methods A total of 55 patients undergoing continuous ambulatory peritoneal dialysis and maintenance hemodialysis in Yunnan Kidney Disease Hospital and The First Affiliated Hospital of Kunming Medical University from October 2014 to December 2015 were chosen. MIS was used to assess the malnutrition inflammation score, using multifrequency bioelectrical impedance in maintenance hemodialysis patients. Hand grip strength was measured and the laboratory index was used to assess the malnutrition of patients. Results There were 26 patients who suffered from the sarcopenia(47.3%), patients with early sarcopenia in 10 cases (18.2%) , patients with sarcopenia in 16 cases (29%), and no sarcopenia in 29 cases(52.7%). The differences of age and gender between the three groups showed statistical significance (P 8). MIS scores had statistically significance and negative correlation with quality of skeletal muscle, skeletal muscle mass index and grip strength(P<0.05). The differences of skeletal muscle, skeletal muscle mass index and grip strength among the three groups had statistically significance (P<0.05). Conclusion Sarcopenia may associate with age and gender. As malnutrition inflammation score increased, the quality of skeletal muscle, skeletal muscle quality index and average of grip strength are on the decline. Improving the state of malnutrition in patients with MHD inflammation may reduce the sarcopenia. Key words: Maintenance hemodialysis; Malnutritionin flammation complex syndrome; Sarcopenia