Convolutional Neural Network in Evaluation of Radiotherapy Effect for Nasopharyngeal Carcinoma

Haifeng Qian,Yancheng Fang,M Pallikonda Rajasekaran

doi:10.1155/2022/1509490

Abstract

This study was aimed to explore the adoption value of magnetic resonance imaging (MRI) under convolutional neural networks (CNN) in the therapeutic effect of nasopharyngeal carcinoma (NPC) radiotherapy. A total of 54 NPC patients were recruited. CNN was employed to perform 3D visualization processing on magnetic resonance (MR) images of NPC patients. MRI changes were analyzed before and after the patient received radiotherapy. The image segmentation and radiotherapy effects of CNN were evaluated by the Recall, intersection over union (IOU), postoperative apparent diffusion coefficient (ADC), and diagnostic coincidence rate. Moreover, gradient vector flow (GVF) algorithm, fuzzy c-means (FCM), and SegNet were adopted for comparative evaluation. Recall of CNN was 94.89% and the IOU was 84.16%, which was remarkably different from other algorithms (P < 0.05). After analysis of the MRI images of patients receiving radiotherapy, ADC of local residual patients was 1.108 ± 0.097 measured by CNN, the ADC was 1.826 ± 0.115, and the missed diagnosis rate was only 7.14%. In summary, CNN had a good effect on the localization and segmentation of NPC patients, and can accurately evaluate the effect of patients receiving radiotherapy, which can assist clinical diagnosis and treatment of NPC.

Highlights

Nasopharyngeal carcinoma (NPC) is a malignant tumor in the mucosa of the nasopharynx
NPC Lesion Detection Model Based on convolutional neural networks (CNN). e CNN was utilized to locate the NPC lesion area, this area was delineated and segmented, and the segmented image area was reduced at the same time
CNN was utilized to outline and segment the lesion sites on NPC magnetic resonance imaging (MRI) images, and the NPC radiotherapy efficacy was judged by MRI images

Summary

Introduction

Nasopharyngeal carcinoma (NPC) is a malignant tumor in the mucosa of the nasopharynx. Most NPC patients are often accompanied by neck mass. They are prone to hearing loss, tinnitus, earache, and recurrent ear infection [3]. E incidence of NPC is the first among head and neck malignant tumors. If the tumor does not disappear six months after surgery, it is residual tumor, and NPC residual or recurrence is the main reason that affects the prognosis and quality of life of patients. Only radiotherapy is utilized, and radiotherapy is mainly combined treatment in the local late stage [6]. With the popularization of intensity-modulated radiation therapy technology and the adoption of comprehensive treatment, the NPC local control rate is more than 90%, and the 5-year survival rate is more than 80%. In contrast to other tumors, NPC treatment has objective efficacy [7, 8]

Methods

Results

Discussion

Conclusion