Abstract
Controlled release of glucose as a model compound through modified chitosan membranes was studied. The chitosan membranes were modified by graft copolymerization of 2-hydroxyethylmethacrylate (HEMA) onto chitosan films using 60 Co γ-ray irradiation. The release characteristics of glucose were studied as a function of degree of grafting. The permeability coefficient of glucose through grafted membranes was found to be in the order 10 −6–10 −7 cm 2/s. The effect of thickness of membranes on the permeability was also determined. Chitosan membranes showed a negligible boundary layer effect. The release of glucose was found to be pH dependent.
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