Abstract

Abstract. Mebendazole (methyl‐5‐benzoyl benziraidazole‐2‐carhamate) was shown to have anthelmintic activity against larvae of Proteocephalus ambloplitis (Leidy) in implantations were found to be highly effective. A single intraperitoneal injection of 200 mg/kg or a capsule implantation of 200 mg/kg of mebendazole each reduced the infection by 95 % after 6 weeks. Oral treatment for 14 consecutive days at 100 mg/kg/ day reduced I he infection by 90%. Intraperitoneal injection of 200 mg/kg of mebendazole ever, did not interfere with spawning and reproduction of largemouth bass; however fish injected with 300 mg/kg produced no fry. Haematocrit, total haemoglobin, total serum protein and histological changes were not evidenl in treated fish.

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