Abstract
Control of breast cancer using metal-containing polymers based on cell line results
Highlights
Metal-containing polymers have shown good activity against MCF-7 and MDA-MB-231 human breast cancer cells
MDA-MB-231 cells are estrogen-independent; estrogen receptor negative while the MCF-7 cells are estrogen receptor (ER+) positive and the combination are used as a matched pair
The focus in the current paper is on Group 4 metallocene, Group 15 and organotin polymers and their ability to control breast cancer
Summary
Metal-containing polymers have shown good activity against MCF-7 and MDA-MB-231 human breast cancer cells. Organotin polymers showed intermediate ability to inhibit breast cancer cell growth. In this paper we introduce cell line data related to the use of metal-containing polymers with reference to controlling the growth of two human breast cancer cell lines.
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