Abstract
The detection of antimicrobial residues in food products of animal origin is of utmost importance. Indeed antimicrobial residues could be present in animal derived food products because of animal treatments for curative purposes or from illegal use. The usual screening methods to detect antimicrobial residues in food are microbiological, immunological or physico-chemical methods. The development of biosensors to propose sensitive, cheap and quick alternatives to classical methods is constantly increasing. Aptasensors are one of the major trends proposed in the literature, in parallel with the development of immunosensors based on antibodies. The characteristics of electrochemical sensors (i.e., low cost, miniaturization, and portable instrumentation) make them very good candidates to develop screening methods for antimicrobial residues in food products. This review will focus on the recent advances in the development of electrochemical aptasensors for the detection of antimicrobial residues in food products. The contribution of nanomaterials to improve the performance characteristics of electrochemical aptasensors (e.g., Sensitivity, easiness, stability) in the last ten years, as well as signal amplification techniques will be highlighted.
Highlights
Antibiotic residues could be present in animal derived-food products because of veterinary treatments for curative or preventive purposes
A label-free multiplex electrochemical aptasensor was developed for the detection of ampicillin and kanamycin based on poly(3,4-ethylenedioxythiophene (PEDOT) as the conductive polymer [137]
Many works have been performed on the development of electrochemical aptasensors for the detection of antimicrobial residues in animal derived food products
Summary
Antibiotic residues could be present in animal derived-food products because of veterinary treatments for curative or preventive purposes. LC-MS/MS methods are increasingly used at the screening step because of their high sensitivity and their ability to identify and quantify the target analytes, even at the screening step. The first developed biosensors for the detection of antimicrobial residues were immunosensors [7]. ELISA tests for the detection of antimicrobial residues were developed previously and so antibodies were already available. Similar benefits can be expected for the development of innovative screening methods for monitoring antimicrobial residues in food products. Different types of aptasensors for the detection of antimicrobials in food products were developed based on three main transduction principles: optical, electrochemical, and mass-sensitive. This review will highlight the main types of nanomaterials used for the development of electrochemical aptasensors for the detection of antimicrobial residues. The role of nanomaterials in the improvement of electrochemical aptasensors performance will be discussed, as well as amplification strategies
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
