Abstract
Uric acid is a product of purine catabolism. The manifestation of hyperuricemia (an increase in the amount of uric acid in the blood) for cells and the entire human body is being studied in connection with new data on the properties of this molecule. Relatively recently, interest in uric acid has ceased to be limited to the "disease of kings" - gout. Currently, more and more studies are investigating the contradictory relationship between uric acid and hypertension. It is believed that uric acid may be involved in the development of oxidative stress, which plays an important role in increasing blood pressure. The argument against this is the strong antioxidant properties of uric acid. It is such an important utilizer of peroxynityrite that it has even given an evolutionary advantage to the human population (unlike other mammals, human serum uric acid concentrations are much higher and normally range from 3 mg / DL to 6 mg / DL). Complex and multidirectional.
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