Abstract
Rampant, irrational and unscientific use of antimicrobials by the healthcare practitioners is adding to the problem of antimicrobial resistance. Therefore, it is of utmost importance to evolve and implement new policies, recommence research actions and pursue steps to manage the crisis of antimicrobial resistance, which can be accomplished by a well-designed Antimicrobial Stewardship programme. A prospective observational study aiming to investigate the use of antimicrobials in Intensive Care Units by means of an AMS programme was carried out in a 400 bedded tertiary level hospital in New Delhi with 140 ICU beds. This evidence-based study looks into the prescription and consumption of antimicrobials, specifically in the ICUs, and attempts to corelate it with the resistance pattern of antimicrobials being used. All the patients being treated with antimicrobials, admitted in the ICUs of the hospital were selected for this descriptive research. Information associated with antimicrobials including the susceptibility pattern of isolates and full dosage regime of each patient from the group was obtained by conducting daily audits for a period of five months. Among the usage of different antimicrobial categories (antibacterial, antifungal and antiviral), the resistance percentage correlation was predominantly focused on the antibacterial. However, the study suggests no conclusive direct or indirect correlation between the usage of an antibacterial (in terms of prescription and consumption) and its resistance, which itself could be a cause of concern for medical practitioners.
Highlights
From the time when first antibiotic, Penicillin, was discovered in 1928 by Alexander Fleming, there had been detection and recognition of antimicrobial resistance (AMR) (Antibiotic / Antimicrobial Resistance, CDC)
It is of utmost importance to evolve and implement new policies, recommence research actions and pursue steps to manage the crisis of antimicrobial resistance, which can be accomplished by a well-designed Antimicrobial Stewardship programme
A prospective observational study aiming to investigate the use of antimicrobials in Intensive Care Units by means of an Antimicrobial Stewardship (AMS) programme was carried out in a 400 bedded tertiary level hospital in New Delhi with 140 ICU beds
Summary
From the time when first antibiotic, Penicillin, was discovered in 1928 by Alexander Fleming, there had been detection and recognition of antimicrobial resistance (AMR) (Antibiotic / Antimicrobial Resistance, CDC). Microorganisms will constantly attempt to tolerate new antimicrobials and share their resistance amongst other microorganisms, which possibly will further result in persistence of infections and dispersal to others (Antibiotic / Antimicrobial Resistance, CDC). There is a tenacious requirement for coordinated efforts to implement new policies, recommence research exertions and pursue steps to manage the crisis of AMR (Spellberg, 2014), which can be accomplished to some extent by a well-designed Antimicrobial Stewardship (AMS) programme. Hypothesis for the purpose of this research is – “the resistance percentage of an antimicrobial is inversely proportional to the number of times it is prescribed by the doctors in the hospital”.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
