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Abstract
AbstractBackground The effect of acyclovir on inpatients with acute herpetic pain has been examined in only few studies.Aim To examine the effect of acyclovir on intensity and course of herpes zoster‐associated neuralgia in hospitalized patients.Method Two groups of patients (50 each) hospitalized for acute herpes zoster in 1983/84 (before acyclovir was available) and in 1989/90 (when acyclovir was given for at least 5 days intravenously) were evaluated for pain and consumption of pain medication.Results The score for pain intensity did not differ significantly in acyclovir‐related patients compared to patients who did not receive the drug.Conclusion This study fails to demonstrate a beneficial effect of acyclovir on acute herpetic neuralgia.
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