Abstract
A clinical need exists for an immunologically compatible surgical patch for the use of soft tissue replacement, body wall repair, and as a wound dressing. Amniotic membrane is a thin light-weight and elastic material and it can promote cell attachment, proliferation and differentiation1. Hyper-dry amniotic membrane as a natural extracellular matrix is a novel dried amniotic, can be preserved at room temperature2and has been used to culture epithelial cell for transplantation. In this study, we made human oral mucosal equivalent using hyper-dry amniotic membrane as a matrix. The cultured oral mucosal equivalent was transplanted in mouse full-thickness skin defect, the wound contraction and characterization of the grafted material was evaluated.
Published Version
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