Abstract
TiO<sub>2</sub> nanotube array films were prepared on porous titanium via anodic oxidation. The morphology and phases of the films were characterized, and the thermal stability, bioactivity <em>In-vitro</em>, biocompatibility <em>in vivo</em>, and osteoinductivity of the films were also studied. It was found the anatase nanotubues give better bioactivity than the amorphous.
Highlights
As is well-known, titanium (Ti) and its alloys are often used in biomaterials because of high strength, toughness and corrosion resistance [14]
The high-porosity porous titanium can match with bone tissues in terms of mechanical properties, and the penetrated hole structures can even offer larger space for tissue growth, offering channels for body liquid flow and nutrition exchange, which are favorable for the inward growth of surrounding cells and new bone growth and strengthen the bio-fixation of bone tissues [5]
To investigate how subsequent treatment affected the performances of porous titanium, we designed three groups: (1) Untreated porous titanium (UPT); (2) Anodically oxidated porous titanium for 1 h at 20 V (APT); (3) Anodically oxidated (1 h at 20 V) and heat-preserved (5 h at 500 °C) porous titanium (HAPT). (Figure 3) shows the surface morphology of different specimens
Summary
As is well-known, titanium (Ti) and its alloys are often used in biomaterials because of high strength, toughness and corrosion resistance [14]. Such alloy tissues have far larger elastic modulus than human bones, which can cause stress shield and bone absorption. The Ti surfaces can be oxidized into a layer of dense oxidation films, which increase the biological inertia of Ti. The binding between Ti and bones belongs to mechanical inter-locking. Surface modification endows Ti and its alloys with bioactivity, so that the new bones can directly bind with the implant surfaces without needing any connective tissues, which directly contributes to osseointegration or bone bonding
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