Abstract
Siderophore is a potential biomarker for pathogen diagnosis. In this study, a siderophore impedance sensor was constructed based on the formation of a siderophore-hemin complex prepared by modification of hemin on an interdigitated array microelectrode. Siderophore reacted with hemin and formed a complex on the electrode surface. As the conductivity of hemin was higher than that of siderophore, the formation of the complex led to decrease of conductivity on electrode surface which was measured by electrochemical impedance spectroscopy. The impedance change of constructed sensor was linear with the concentration of siderophore between 1 nM and 100 µM, with a limit of detection of 0.86 nM. The detection time was less than 15 min. When the sensor was used to analyze medium, the recovery was between 86.7% and 102.8%. Compared with conventional methods for siderophore, this approach is faster, more sensitive, and has potential application for the determination of pathogens.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
