Constitutive single nucleotide polymorphisms (SNP) assessment for predicting tolerability and efficacy of triplet hepatic artery infusion (HAI) and intravenous cetuximab (IV-CET) in patients (pts) with liver metastases from colorectal cancer (LM-CRC) (European trial OPTILIV, NCT00852228).

Francis Levi,Carlos Carvalho,Pasquale F Innominato,Gerard A Milano,Antoinette Lemoine,Michel Ducreux,C N J Focan,Denis Michel Smith,Marie-Christine Etienne-Grimaldi,Simon Pernot,Rene Adam,Elodie Peyric,Abdoulaye Karaboué,Rosine Guimbaud,Mohamed Bouchahda,Mohamed Hebbar,Raphaël Saffroy

doi:10.1200/jco.2014.32.15_suppl.3593

Constitutive single nucleotide polymorphisms (SNP) assessment for predicting tolerability and efficacy of triplet hepatic artery infusion (HAI) and intravenous cetuximab (IV-CET) in patients (pts) with liver metastases from colorectal cancer (LM-CRC) (European trial OPTILIV, NCT00852228).

Francis Levi, Carlos Carvalho + Show 15 more

https://doi.org/10.1200/jco.2014.32.15_suppl.3593

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Journal: Journal of Clinical Oncology

Publication Date: May 20, 2014

Affiliation: Inserm, Hospital Prof. Dr. Fernando Fonseca, Hôpital Paul-Brousse, Institut Gustave Roussy, Clinique Saint-Joseph, Hôpital Saint-André, Centre Antoine Lacassagne, Hôpital Européen, Hôpital Européen Georges-Pompidou, Queen Mary University of London, Hôpital Purpan, Hôpital Claude Huriez

#Liver Metastases From Colorectal Cancer #Hepatic Artery Infusion #Intravenous Cetuximab #Single Nucleotide Polymorphisms #Efficacy Of Cetuximab #Liver Metastases #Colorectal Cancer #Wt KRAS #European Trial #Artery Infusion

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3593 Background: The combination of IV-CET and HAI of irinotecan , oxaliplatin and 5-fluorouracil displayed high activity as 2-4thchemotherapy line for initially unresectable wt KRAS LM-CRC, yieldi...

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Constitutive single nucleotide polymorphisms (SNP) assessment for predicting tolerability and efficacy of triplet hepatic artery infusion (HAI) and intravenous cetuximab (IV-CET) in patients (pts) with liver metastases from colorectal cancer (LM-CRC) (European trial OPTILIV, NCT00852228).