Abstract
Nonspecific granuloma of the larynx is a benign tumor that usually occurs on the posterior glottis. Conventional treatment for this laryngeal lesion has consisted of surgical resection. However, this lesion has a strong tendency to recur postoperatively and may require multiple repeated operative procedures. Conservative treatment, consisting mainly of beclomethasone dipropionate inhalation therapy, was instituted in 20 cases with good results. We discussed the effect of beclomethasone dipropionate on this lesion as well as the etiology of this disease.
Highlights
The subjects included 3 patients with post-intubation granuloma that developed after endotracheal intubation and 17 patients with idiopathic granuloma unrelated to endotracheal intubation
Fair: Reduction in size of the lesion within 3 months, but residual lesion observed after 6 months of inhalation therapy
Surgical resection has been the treatment of first choice
Summary
Nonspecific granuloma of the larynx is a benign tumor that usually occurs on the posterior glottis. Recurrences frequently occur even when these granulomas are surgically resected and it is not rare for multiple repeated operations to be required. Conservative treatment using primarily a beclomethasone dipropionate inhaler (Aldecine(R) inhaler) was instituted in 20 cases of nonspecific granuloma of the larynx with good results. Metropolitan Ohtsuka Hospital in the 7 years between April 1988 and March 1995, the 20 patients who underwent conservative therapy and were followed up for 6 months were selected as subjects of this study. Clinical characteristics and therapeutic results of these patients were evaluated (Table I). Median patient age at time of the TABLE Clinical characteristics and therapeutic results of beclomethasone dipropionate inhalation therapy
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