Abstract
Reduction of Ca 2+ current amplitude by the Conus peptide ω-conotoxin-MVIID (ω-CTx-MVIID) was measured in voltage-clamped, goldfish retinal ganglion cells. Effects of depolarizing shifts in holding potential, and sequential applications of ω-CTx-MVIID, ω-CTx-GVIA, and BAY-K-8644, together with effects of Ni 2+ and ω-Aga-IIA, indicate that ω-CTx-MVIID may target Ca 2+ channels differing from those termed T, L, N, P, Q and R. Copyright © 1996 Elsevier Science Ltd
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