Connectomic disturbances in schizophrenia

Abstract

Event Abstract Back to Event Connectomic disturbances in schizophrenia Alex Fornito1, 2* 1 University of Melbourne, Melbourne Neuropsychiatry Centre and Centre for Neural Engineering, Australia 2 NICTA Victorian Research Laboratory, Australia Accumulating evidence indicates that schizophrenia is not caused by focal pathology in a single, specific brain region. Rather, it arises from disordered interactions within and between distributed neural circuits. In other words, it is a disorder of brain connectivity. A great deal of insight into the pathophysiology of the disorder can therefore be gained from recent attempts to map the human connectome–the complete set of neural elements and connections comprising the brain. This talk will overview some of the basic concepts and methods of the burgeoning field of human connectomics and illustrate how these techniques can be used to characterize disruptions at either the level of specific neural circuits or the entire brain in patients with schizophrenia. Many of these changes have a genetic basis, suggesting that they represent viable risk biomarkers for the disorder. Keywords: Schizophrenia, brain imaging, connectomics, biomarkers, brain connectivity Conference: ACNS-2012 Australasian Cognitive Neuroscience Conference, Brisbane, Australia, 29 Nov - 2 Dec, 2012. Presentation Type: Symposium Presentation Topic: Other Citation: Fornito A (2012). Connectomic disturbances in schizophrenia. Conference Abstract: ACNS-2012 Australasian Cognitive Neuroscience Conference. doi: 10.3389/conf.fnhum.2012.208.00009 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 17 Oct 2012; Published Online: 26 Oct 2012. * Correspondence: Dr. Alex Fornito, University of Melbourne, Melbourne Neuropsychiatry Centre and Centre for Neural Engineering, Melbourne, Australia, fornitoa@unimelb.edu.au Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Alex Fornito Google Alex Fornito Google Scholar Alex Fornito PubMed Alex Fornito Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.