Abstract
Conjugated linoleic acid or CLA, is among the bioactive components which are interesting for obesity treatment. It is a term that includes a conjugated isomer group of the linoleic acid, of which two of them cis-9, trans-11 and trans-10, cis-12 are capable of reducing body fat in animals and human beings. The best source of CLA in food is found in meat and dairy, which come from ruminants. The anti-obesity effect of the CLA has been demonstrated by the reduction on the indicators of the obesity, as body fat and waist circumference. Although the effect of CLA on the reduction of body fat is well known, it is important to make a distinction in the condition of patients and the consumed dose because CLA also has modified other cardiovascular risk markers. While the CLA intake has showed a positive effect and less cardiovascular related risk factors, also has increased the insulin resistance in type 2 diabetes mellitus patients. Therefore, the purpose of the present text was to review the most important aspects about the CLA intake in humans, like the dietary sources, the action mechanism and the clinical results.
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