Congenital Toxoplasmosis: Current Brazilian public health policy

Abstract

Event Abstract Back to Event Congenital Toxoplasmosis: Current Brazilian public health policy Rogerio S. Vaz1* 1 Complexo Pequeno Principe, Brazil Toxoplasmosis is caused by the protozoan parasite, Toxoplasma gondii. In pregnant women, the prenatal diagnosis should be made as early as possible, so that therapy may be applied to reduce parasitemia and avoid transplacental infection. Despite the high prevalence of infected individuals around the world (20-90%) in Brazil, seroprevalence may vary between 40% and > 80%, reflecting a significant disparity between the public health policies and resources applied in the different regions of the country and the human development index (HDI) of each of them. The lack of consistent and periodical data on seroprevalence per region makes it difficult to understand the significance of this infection and to plan specific public health policies and strategies. Regarding basic and clinical research, toxoplasmosis is not a priority if compared to the allocation of government funds and incentives to other tropical illnesses, such as: Chagas disease, Leishmaniasis, Dengue fever. There are also few study groups in Brazil that focus in this basic area, for genomics and proteomics studies of T. gondii strains-for the design of new methods of diagnosis, antiparasitic drugs and a vaccine model for humans and animals. This study highlights, taxonomic and epidemiologic aspects, diagnosis methods, treatment and technical-scientific aspects of Toxoplasma gondii and toxoplasmosis in the Brazilian context. References Castilho-Pelloso, M.; Falavigna, D. L. M; Falavigna-Guilherme, A. L. (2007) Suspected acute toxoplasmosis in pregnant women. Rev Saúde Pública., 41(1):27-34. Lopez, A, Dietz VJ, Wilson M, Navin TR, Jones J. L. Preventing Congenital Toxoplasmosis. M M W R–Recommendations and Reports. v. 49, (RR02), p. 57-75, 2000. Martins-Duarte, E. S.; Lemgruber, L.; Souza, W.; Vommaro, R. C. (2010) Toxoplasma gondii: Fluconazole and itraconazole activity against toxoplasmosis in a murine model. Experimental Parasitology 124, P. 466-469. Martins-Duarte, E. S.; Lemgrubera, L.; Lorente, S. O.; Gros, L.; Magaraci, F.; Ian H. Gilbert, Wanderley de Souzaa, Rossiane C. Vommaroa. (2011) Evaluation of three novel azasterols against Toxoplasma gondii. Veterinary Parasitology 177 p.157-161. Neto, C.N.; Amorim, F.; Lago, E. G. (2010) Estimation of the regional distribution of congenital toxoplasmosis in Brazil from the results of neonatal screening. Sci. Med, v. 20, n.1, p. 64-70. Spalding, S. M.; Amendoeira, M. R. R.; Ribeiro, L. C.; Silveira, C.; Garcia, A. P. E Camillo-Coura, L. Estudo prospectivo de gestantes e seus bebês com risco de transmissão de congenital toxoplasmosis em município do Rio Grande do Sul. Rev da Soc Bras de Med Trop. v. 36, n. 4, p. 483-491, 2003. Vaz et al. Technical evaluation of serological screening tests for anti-Toxoplasma gondii Antibodies to prevent unnecessary transfusion risks. Rev Bras Hematol Hemoter. 2008; v. 30, 277-280 Vaz et al., 2010. Serological prevalence of Toxoplasma gondii antibodies in pregnant womenFrom Southern Brazil. Parasitol Res (2010) 106:661-665. Vaz, R. S. Diagnóstico sorológico, isolamento e caracterização molecular de Toxoplasma gondii (Nicole & Manceaux, 1909) em mulheres gestantes atendidas pelo serviço público na cidade de Curitiba. (SERODIAGNOSTIC, ISOLATION AND MOLECULAR CHARACTERIZATION OF Toxoplasma gondii IN PREGNANT WOMEN ATTENDED BY PUBLIC HEALTH SERVICES IN THE CITY OF CURITIBA. http://www.ppgbiotec. ufpr.br/tes_teses.php Tese: Doutorado–Universidade Federal do Paraná. Setor Tecnológico. Pósgraduação em Processos Biotecnológicos. 2006 Keywords: seroepidemiology, Toxoplasmosis, Public Health, Pregnancy, Risk factors Conference: 15th International Congress of Immunology (ICI), Milan, Italy, 22 Aug - 27 Aug, 2013. Presentation Type: Abstract Topic: Host-pathogen interactions Citation: Vaz RS (2013). Congenital Toxoplasmosis: Current Brazilian public health policy. Front. Immunol. Conference Abstract: 15th International Congress of Immunology (ICI). doi: 10.3389/conf.fimmu.2013.02.00428 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 31 Mar 2013; Published Online: 22 Aug 2013. * Correspondence: Dr. Rogerio S Vaz, Complexo Pequeno Principe, Curitiba, Paraná, 80230-020, Brazil, rogerio.vaz@fpp.edu.br Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Rogerio S Vaz Google Rogerio S Vaz Google Scholar Rogerio S Vaz PubMed Rogerio S Vaz Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. 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