Congenital anomalies in newborns of mothers exposed to teratogenic agents during pregnancy

Abstract

Congenital modifications are characterized by an interaction between chemical, physical agents or pathogenic organisms, with the embryo in formation, with or without hereditary influence, being conceptualized mainly by changes in cell growth and multiplication, which are called teratogenic agents. . The study aimed to search the literature for the relationship between the main teratogenic agents and fetal congenital anomalies. This is a systematic review of the literature, in which a search was carried out in the following databases: LILACS and BDENF via VHL; MEDLINE via Pubmed, and the Scielo portal. Articles published between 2017 and 2022 were used. Anomalies resulting from teratogens are mostly avoided with an effective monitoring and health education process in the prenatal period. However, research has shown that the main teratogenicities are due to pharmacological agents. The study serves as a warning to pregnant women, as well as an incentive to build new research within the theme.