Abstract

Reactions of 3-acyl-1,2-naphthoquinones with ethyl mercaptoacetate followed by protection of the resulting hydroxyl groups and thiophene ring formation using 1-trimethylsilylimidazole, deprotection with hydrochloric acid,and oxidation with cerium(lV) ammonium nitrate (CAN) gave, in one-pot, the title thienonaphthoquinone derivatives in moderate to good yields.

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