Abstract
We read with great interest the report by Korosoglou et al, 1 Korosoglou G. Humpert P.M. Halbgewachs E. Bekeredjian R. Filusch A. Buss S.J. Morcos M. Bierhaus A. Katus H.A. Nawroth P.P. Kuecherer H. Evidence of left ventricular contractile asynchrony by echocardiographic phase imaging in patients with type 2 diabetes mellitus and without clinically evident heart disease. Am J Cardiol. 2006; 98: 1525-1530 Abstract Full Text Full Text PDF PubMed Scopus (31) Google Scholar “Evidence of Left Ventricular Contractile Asynchrony by Echocardiographic Phase Imaging in Patients With Type 2 Diabetes Mellitus and Without Clinically Evident Heart Disease,” in which it was noted that asynchrony was significantly greater in patients with diabetes mellitus than in controls and significantly lower than in patients with left bundle branch block, that tissue Doppler imaging was correlated with echocardiographic phase imaging but was more time consuming and showed greater intraobserver variability, and that this was the first study showing increased left ventricular asynchrony in patients with diabetes mellitus and no clinical evidence of heart disease. The methods and interpretation of the results, however, raise several concerns. ReplyAmerican Journal of CardiologyVol. 99Issue 10PreviewWe thank Song and Ma1 for their interest in and comments on our report, “Evidence of Left Ventricular Contractile Asynchrony by Echocardiographic Phase Imaging in Patients With Type 2 Diabetes Mellitus and Without Clinically Evident Heart Disease.”2 The central finding of our report involves the early presence of left ventricular (LV) asynchrony as a distinct clinical entity in otherwise healthy patients with well-controlled type 2 diabetes mellitus (T2DM). As mentioned in our original report, we included patients with T2DM who showed no evidence of heart disease and no microalbuminuria, as a marker of cardiovascular risk. Full-Text PDF
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