Abstract
Background: Aim of this study, is to correlate the ayurvedic concept of ranjak pitta with its modern science counterpart. Methods: analysis of ranjak pitta according to ayurvedic literature and comparing or correlating it with similar functional modern science parameter with the help of modern science literature. Ranjak pitta is type of pitta who with help of rasa dhatvagni (type of metabolic power) colours rasa dhatu (plasma) red to convert it in rakta dhatu(blood). Discussion: After analysing both ayurvedic and modern science literature the action of ranjak pitta stated in ayurvedic texts can be correlated to combine action of ferrochelatase, apotransferrin, transferrin, apoferritin, ferritin. Conclusion: Combine action of ferrochelatase, transferrin, apotransferrin, ferritin, apoferritin is similar to action of ranjak pitta, hence they can be considered as single acting principle.
Highlights
Ayurveda is ancient science based majorly on observations
Combine action of ferrochelatase, transferrin, apotransferrin, ferritin, apoferritin is similar to action of ranjak pitta, they can be considered as single acting principle
Ranjak pitta is type of pitta which converts rasa dhatu into rakta dhatu by clouring it red with the help of rasa dhatvagni
Summary
The function of ranjak pitta is similar to combined action of Ferrochelatase, transferrin, ferritin, apotransferrin & apoferritin. On the basis of aboce conclusion ranjak pitta can be classified in active and inactive forms. Conversion of ranjak pitta from inactive to active form is governed by hepcidine and ferroportin. Sthana of ranjak pitta (location) can be stated as - bone marrow, plasma, liver(hepatocytes &. Ranjak pitta colours rasa dhatu and converts into rakta dhatu by means of formation of ‘heme’. This action took place in bone marrow. Skeletal muscles) in red colour, by forming ‘heme’ component of myoglobin. Increase in Ranjak pitta can lead to darkening of skin, hepatomegaly, spleenomegaly, liver disorders. That signifies its presence in liver, spleen and skin
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