Abstract
Simple SummaryIrisin and myostatin are regulatory proteins produced by muscle cells. The aim of the study was to evaluate the effect of exercise on plasma irisin and myostatin concentrations in horses in different types of training (speed versus endurance). To find out, we tested 20 Arabian horses, submitted to the two different equestrian disciplines, and consequently different training regimes. The first group of horses realized a short-term, high-speed bout of exercise whereas the second group of horses were submitted to long-lasting, endurance effort. The obtained results showed that the single bout of exercise induced an increase in plasma myostatin concentration. Plasma irisin level decreased during the race season in racehorses. This means that irisin and myostatin may play a regulatory role in the maintenance of the energy balance processes. Skeletal muscle is considered to be the largest endocrine organ determining the maintenance of energy homeostasis. Adaptive changes in skeletal muscles in response to physical exercise influence the production as well as secretion of myokines, which are bioactive factors that play a crucial role in energy expenditure processes. The aim of the study was to investigate the impact of two different types of exercise on the circulating level of two of these, myostatin and irisin, in trained horses. Twenty purebred Arabian horses were involved in the study: 10 three-year-old horses trained on the racetrack and 10 endurance horses aged 7.4 ± 1.9 years. The horses from both groups were regularly trained throughout the entire season, during which they also participated in Polish National competitions. To assess the influence of the training sessions on plasma myostatin and irisin concentrations, blood samples taken at rest and 30 min after the end of exercise were analyzed. In the studied horses, the single bout of exercise did not influence plasma irisin but induced an increase in plasma myostatin concentration. In racehorses, plasma irisin concentration decreased with the length of the training season. Plasma myostatin was higher in endurance horses than in three-year-old racehorses. Lack of exercise-induced fluctuation in circulating irisin in studied horses suggests that myostatin released in response to exercise provides a negative feedback signal to irisin release.
Highlights
Exercise is essential for improving both the general musculoskeletal fitness and athletic performance of sport horses [1,2,3]
The aim of the study was to evaluate the effect of exercise on changes in plasma myostatin and irisin concentrations in horses in different types of training
The results of our study showed that the highest resting values of myostatin were recorded in endurance horses, which were older than the racehorses
Summary
Exercise is essential for improving both the general musculoskeletal fitness and athletic performance of sport horses [1,2,3]. A properly maintained training regime improves the efficiency of the musculoskeletal system and ensures energy homeostasis during intensive muscular work [7] This is important as skeletal muscle is responsible for about. Muscle tissue is considered to be the largest endocrine organ determining the maintenance of energy homeostasis [9,10,11] This is based on detailed analyses of the secretory function of muscle tissue, which revealed that a complex of over 300 protein agents are actively secreted by skeletal myocytes [12,13]. They should be considered as specific messengers that allow communication between muscles and other organs such as adipose tissue, liver, bone, and the nervous system in order to produce the beneficial effects of exercise at the whole-body level [14,15,16,17]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
