Abstract
Background IL17 is a cytokine produced by activated helper lymphocytes Th17. It plays a role in the mechanisms of allergic reactions involving neutrophils through the induction of poduction cytokines and chemokines. Affects the activation, recruitment and migration of neutrophils into the tissue by regulating inflammatory reaction. Activated neutrophils secrete elastase and ROS (reactive oxygen derivatives) important mediators of the inflammatory process responsible for tissue damage.
Highlights
IL17 is a cytokine produced by activated helper lymphocytes Th17. It plays a role in the mechanisms of allergic reactions involving neutrophils through the induction of poduction cytokines and chemokines
Analyses: Interleukin 17A concentrations in serum, neutrophil elastase concentration in serum, ROS production by unstimulated neutrophils, the relation between serum levels of IL17A and metabolic activity of neutrophils measured by chemiluminescence assay, and serum elastase
Concentration was determined by ELISA using IL17A sets eBioscience and elastase with sets BENDERMED SYSTEMS
Summary
IL17 is a cytokine produced by activated helper lymphocytes Th17. It plays a role in the mechanisms of allergic reactions involving neutrophils through the induction of poduction cytokines and chemokines. Concentration of interleukin 17A and measurement properties of the neutrophiles with food allergy hypersensitivity patients M Żbikowska-Gotz*, K Pałgan, E Gawrońska-Ukleja, A Kuźmiński, M Przybyszewski, Z Bartuzi From Food Allergy and Anaphylaxis Meeting (FAAM 2013) Nice, France.
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