Abstract
Aim: Within this work, a comparative analysis of two commercial computer-aided detection or diagnosis (CAD) systems, CyclopusCAD® mammo (v. 6.0) produced by CyclopusCAD Ltd (Palermo, Italy) and SecondLook® (v. 6.1C) produced by iCAD Inc. (OH, USA) is performed by evaluating the results of both systems application on an unique set of mammographic digital images routinely acquired in a hospital structure. Materials & methods: The two CAD systems have been separately applied on a sample set of 126 mammographic digital cases, having been independently diagnosed by two senior radiologists. According to the human diagnosis, the cases in the sample reference set are divided into 61 negatives and 65 pathological cases (21 cases displaying both mass lesions and microcalcifications and 44 cases characterized only by mass lesions). The images in the pathological subset contain 123 human diagnosed mass lesions and 37 human diagnosed microcalcifications clusters. In the case of CyclopusCAD, the system offered the poss...
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