Abstract

To explore the application value of the reconstruction algorithm based on an iterative algorithm in the analysis of CT image and analyze the therapeutic effect of honey-fried Herba Ephedrae combined with Western medicine on acute exacerbation chronic obstructive pulmonary disease (AECOPD), a total of 96 AECOPD patients admitted to our hospital from January 2018 to December 2019 were selected as research subjects. According to a different treatment method, the subjects were divided into a control group (Ctrl group, conventional therapy) and an observation group (OG, conventional therapy + honey-fried Herba Ephedrae), with 48 in each group. The CT image algorithm was established based on the iterative algorithm, and the CT dose indexes of the reconstruction algorithm and the Filtered Back Projection (FBP) algorithm under the same conditions were compared ( P < 0.05 ). After using CT to confirm the diagnosis of the subjects, the difference in indicators of forced expiratory volume in one second (FEV1), forced expiratory volume in one second to forced vital capacity ratio (FEV1%), and forced vital capacity (FVC), inflammatory factors of serum interleukin-8 (IL-8), serum interleukin-10 (IL-10), and tumor necrosis factor (TNF-α), the bronchial wall area, and the total treatment efficiency before and after different treatment was analyzed. The results suggested that the Computed Tomography Dose Index (CTDI) of iterative reconstruction (IR) algorithm when scanning different parts was higher than that of the FBP algorithm. The pulmonary function indexes and the expression of IL-8 and TNF-α in the OG were higher than those in the Ctrl group ( P < 0.05 ); the bronchial wall area, bronchial wall area percentage, and IL-10 expression in the OG were all lower than those in the Ctrl group ( P < 0.05 ). The effectiveness and improvement rates of the Ctrl group were 47.92% and 25%, respectively, significantly lower than those in the OG group, 56.25% and 31.25% ( P < 0.05 ), and the total efficiency of the observation group was 87.5%, which was significantly higher than that in the Ctrl group (72.92%) ( P < 0.05 ). In conclusion, based on the iterative algorithm, a CT reconstruction algorithm with better noise reduction performance was established, and the use of honey-fried Herba Ephedrae combined with Western medicine can improve the effective rate of treatment.

Highlights

  • Chronic obstructive pulmonary disease (COPD) is a chronic disease caused by toxic particles/gas with dyspnea as the main symptom, and the deaths in China account for 31.1% of the total worldwide [1]

  • A total of 96 acute exacerbation chronic obstructive pulmonary disease (AECOPD) patients admitted to our hospital from January 2018 to December 2019 were selected; 48 of them were rolled into a Ctrl group, and the rest were rolled into an OG according to random sampling method. e Ctrl group was treated with conventional treatment methods such as anti-infection, antiinflammatory, and bronchodilator according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) (2018) standard [14], and the OG accepted honey-fried

  • Under the same dose reduction level and the same tube voltage (120 kV), when the head, sinuses, chest, abdomen, lumbar spine, and blood vessels were scanned by iterative reconstruction (IR) algorithm, the tube current had an obvious difference in contrast with the Filtered Back Projection (FBP) algorithm (P < 0.05) (Figure 2). e Computed Tomography Dose Index (CTDI) was further compared under the same conditions, and the CTDI of the IR algorithm was higher than that of the FBP algorithm when scanning different parts (Figure 3)

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Summary

Introduction

Chronic obstructive pulmonary disease (COPD) is a chronic disease caused by toxic particles/gas with dyspnea as the main symptom, and the deaths in China account for 31.1% of the total worldwide [1]. AECOPD is an acute onset process in the course of COPD, and patients will experience severe respiratory airflow obstruction. E most common cause of AECOPD is respiratory infection [2]. The AECOPD is treated mainly by drugs, and most of the commonly used drugs are Western medicine, including respiratory stimulants, bronchodilators, glucocorticoids, Scientific Programming and antibacterial and anti-inflammatory drugs [4]. The combined treatment of Chinese medicine and Western medicine has become a trend in the treatment of AECOPD. Some studies have combined ephedra mains with other traditional Chinese medicines to treat COPD, with good effect [7], but few studies have combined ephedra mains with Western medicine to treat AECOPD

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