Abstract
Thiazolidi-4-one is a significant pharmacophore and has been known to exhibit a diverse range of biological activities for a long time. A new compound (6), thiazolidi-4-one was synthesized and characterized by spectroscopic techniques and X-ray single crystal structure. The stereochemistry of compound (6) was determined theoretically (DFT level) and experimentally (single crsytal X-ray structure) both. The DNA binding ability of the compound 6 has been assessed as using UV–Visible absorption studies and docking studies, MTT-assay study on MCF-7 cell line revealed non-toxic nature of the compound (6) in the concentration range 10–320μM.
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