Abstract
A 3D heart model is proposed to simulate the effect of bundle branch blocks in human heart. This model consists of the ventricle model with the electrophysiological approximation of the cells. The computational approach to cardiac cells is based on the electrophysiological model of the human ventricular myocytes proposed by ten Tusscher et al. (2004). The 3D geometry of human heart tissue is discretized to a finite element mesh system for the simulation of electric wave propagation using a monodomain method. Purkinje fibers in ventricles are modeled based on an anatomical structure with simplified model of electric conduction. Using the proposed human heart model we simulated the electrophysiological effects of BBB (bundle branch block) in cardiac tissue. Computational results showed that the BBB induces the changes of electric wave conduction pattern and pseudo-ECG signal compared with normal heart.
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