Comprehensive treatment of acne patients with gastroduodenal pathology and manifest herpesvirus infection

Abstract

Objective -increasing the efficiency of treatment of acne patients by using anti-Helicobacter, antiviral and immunotropic drugs in their complex therapy, taking into account the clinical features of dermatosis, identifying concomitant H. pylori diseases and associated mani­festations of herpes simplex type I and II and individual indicators of systemic immunity. Material and methods. 134 acne patients aged 18 to 30 years, among which 74 women and 60 men, were under the supervision. In patients with acne, the presence of concomitant H. pylori and manifest herpes virus infection, as well as individual immunological parameters by known methods, were in­vestigated. Results. We have established the incidence of concomitant H. pylori and herpes manifest infection, their effect on the clinical course of dermatosis, quality of life and immune status of patients and, based on this, we worked out measures to improve their comprehen­sive treatment by means of anti-Helicobacter (amoxi­cillin, clarithromycin), antivirus (inosine pranobex) and immunotropic (thymalin) drugs that improve significantly immediate and long-term results of acne treatment in these patients. Conclusions. The developed improved methods for the treatment of acne patients, taking into account the presence of concomitant H. pylori - associ­ated diseases and manifest forms of herpes virus infec­tion, changes in systemic immunity and the clinical fea­tures of dermatosis, can improve both the immediate and long-term results of acne treatment, which is confirmed by the reliable positive dynamics of the studied clinical and laboratory indicators.