Compositional and temporal changes of the gut microbiome in women with cervical cancer undergoing chemoradiation: Does it predict response?

T.T Sims,L.E Colbert,T Karpinets,G.W.G Biegert,A.Y Delgado,M.P Mezzari,T Solley,K Yoshida-Court,A Mitra,L.L Lin,L.M Ramondetta,A.A Jazaeri,M Frumovitz,A Jhingran,K Schmeler,J Wargo,A.H Klopp

doi:10.1016/j.ygyno.2020.06.074

Compositional and temporal changes of the gut microbiome in women with cervical cancer undergoing chemoradiation: Does it predict response?

T.T Sims, L.E Colbert + Show 15 more

https://doi.org/10.1016/j.ygyno.2020.06.074

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Journal: Gynecologic oncology

Publication Date: Oct 1, 2020

Affiliation: The University of Texas MD Anderson Cancer Center, Baylor College of Medicine

#Gut Microbiome In Women #Microbiome In Women + Show 8 more

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Abstract

Objective: The gut microbiome may influence response to various cancer therapeutics, and its application in cervix cancer (CC) is lacking. This study aimed to assess the effect of chemoradiation (CRT) on the gut microbiome and to examine the association between the gut microbiome and clinical outcomes in women with CC undergoing CRT.

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