Abstract

The aim of our work was to carry out a comparative analysis of the essential oils of shoots and leaves of Laurus nobilis L. Ukrainian flora and to determine the prospects for their use in pharmacy.
 Materials and methods. Raw materials for obtaining essential oil (shoots and leaves) of Laurus nobilis L. were harvested in November 2017 in the southern regions of Ukraine.
 By the method of chromatography-mass spectrometry using an Agilent Technology 6890N chromatograph, the component composition of 4 samples of essential oil of Laurus nobilis L. raw material was investigated and identified.
 The composition of the essential oil was identified by comparing the results with the data from the NIsT 02 mass spectra library (more than 174,000 substances).
 Results. Thus, in the studied series of the essential oil of the shoots, a similarity was observed both in the set of components and in the relative content of a number of individual compounds and compounds of structurally related groups. The content in these samples was dominated by 1,8-cineole (19.63 % of the amount and 12.93 % of the amount, respectively), α-terpinyl acetate (16.22 % of the amount and 16.03 % of the amount, respectively).
 In contrast to the series of the essential oil of the shoots, the component composition of the essential oil of the leaves of the two series was significantly different. In both studied series, only 3 compounds were identified that are common - these are aromatic compounds methyleugenol, trans-methylisoevgenol, and the sequiterpenoid caryophyllene oxide.
 Conclusions. Thus, a comparative analysis of the component composition of biologically active substances in the essential oils of shoots and leaves of the Laurus nobilis L. Ukrainian harvest showed the prospects for further pharmacognostic research of this plant as a source of medicinal raw materials

Highlights

  • The search for new medicinal plants and expanding the range of herbal medicines is one of the top priorities of the pharmaceutical industry of any country, Ukraine is no exception

  • The essential oil of two samples of shoots of different growth places was studied, because it is known from literature sources that shoots, in addition to leaves and fruits, are a source of essential oil

  • The study revealed that the component composition of the essential oil of both studied series of shoots is similar in both the set of components and the relative content of a number of individual compounds and compounds of structurally related groups

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Summary

Introduction

The search for new medicinal plants and expanding the range of herbal medicines is one of the top priorities of the pharmaceutical industry of any country, Ukraine is no exception. Attention is drawn to those plants that have long been used in folk medicine, are widespread in a particular area, and this is accompanied by an insufficient degree of study Such a representative of the flora is Laurus nobilis L. of the family Lauraceae [1]. In the essential oil of raw Laurus nobilis L. from Turkey (leaves) [5], Iran (leaves) [8], Bulgaria (leaves, shoots, fruits) [9] and Montenegro (leaves, shoots, fruits) [10] common and main components were 1,8-cineole, sabinene and α-terpinyl acetate, but in the leaves of Laurus nobilis L. from Southern Italy the content of α-terpinyl acetate was negligible [11]. The significant content of linalool is characteristic of the essential oil of Laurus nobilis L. leaves from Southern Italy, Bulgaria and Montenegro. The composition of the essential oil depends on the place of growth of the plant, the method of production and method of storage

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