Abstract
We explored the effects of different levels of compliance with an enhanced recovery after surgery (ERAS) protocol on the short-term prognosis of patients who underwent colorectal cancer surgery. We conducted a single-center prospective cohort study in which 254 patients who received surgical treatment in a teaching tertiary care hospital were enrolled from March 2016 to November 2016. The patients were divided into four groups (I, II, III, and IV) based on individual compliance rates; the corresponding range of compliance rates was 0-60%, 60-70%, 70-80%, and 80-100%, and the number of patients in each group was 66, 63, 53, and 72, respectively. In the four groups from low to high compliance with ERAS (group I, II, III, and IV), the incidence of surgical site infections was 24.2%, 20.6%, 9.4%, and 6.9% (P < 0.05); the overall incidence of postoperative complications was 41.3%, 33.3%, 26.4%, and 16.7% (P < 0.05); the median length of postoperative hospital stay (in days) was 12.5, 10, 9, 8 (P < 0.05); and the median total hospital cost (Chinese Yuan) was 71,733, 73,632, 65,861, and 63,289 (P < 0.05), respectively. These results suggest that higher compliance with the ERAS protocol was associated with a lower incidence of surgical site infections, lower overall postoperative complication rate, shorter postoperative hospital stays, and lower total hospital costs.
Highlights
Colorectal cancer is the second most common cancer in females and the third most common in males, with an estimated 0.69 million cancer-related deaths occurring in 2012 worldwide [1]
We explored the effects of different levels of compliance with an enhanced recovery after surgery (ERAS) protocol on the short-term prognosis of patients who underwent colorectal cancer surgery
The rate of compliance with the ERAS protocol was associated with the short-term prognosis of patients
Summary
Colorectal cancer is the second most common cancer in females and the third most common in males, with an estimated 0.69 million cancer-related deaths occurring in 2012 worldwide [1]. An increasing number of studies have confirmed that the enhanced recovery after surgery (ERAS) protocol has the advantages of reducing the length of postoperative hospital stay after colorectal surgery without compromising patient safety and even reduced the incidence of postoperative complications [2,3,4,5,6]. Professors Kehlet and Wilemore formally promoted the concept of ERAS in 2001, and it is widely used in the surgical field [9, 10]. Through the establishment of an ERAS team to promote multi-disciplinary cooperation, good clinical outcomes have been achieved in the forms of reduced incidence of postoperative complications and reduced postoperative hospital stays; these findings support the cost-effectiveness of ERAS [11,12,13]. The ERAS protocol of colorectal cancer surgery is the most widely used
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call