Abstract

Compliance to company based colorectal cancer screening in Germany using fecal immunochemical test (FIT) - Results of Almost Half a Million FIT tests

Highlights

  • Screening for colorectal cancer (CRC) is encouraged worldwide

  • Gemany, Abstract Background Despite the existence of the statutory early cancer detection program in Germany and the removal of financial barriers, which is frequently reported in the literature to be the main obstacle in screening, uptake of colorectal cancer screening remains quite low

  • The positive predictive values (PPV) for cancer aged between 55 and 74 was 4.6% for men and women, but 22% for men and 8% for women (95%CI: 3.63%12.26%) for advanced adenomas

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Summary

Introduction

Screening for colorectal cancer (CRC) is encouraged worldwide. it is eligible for early detection due to the long preclinical phase of the disease. According to the statutory early cancer detection program in Germany (Das gesetzliche Früherkennungsprogramm) [1], all insured individuals are entitled to undergo colorectal cancer screening with a yearly guaiac-based occult blood stool test (gFOBT) starting at age 50 and a colonoscopy starting at 55 years, which may be repeated after 10 years if the findings are unremarkable. They may opt for a biennial gFOBT, which is standard screening in many countries. Opponents argue that most people undergoing screening are neither identified as having cancer nor protected from its developing [8]

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