Abstract
A 73-year-old man with histopathologically confirmed diffuse large B-cell lymphoma underwent both 18F-FDG and 18F-FAPI PET/CT. Although 18F-FDG PET showed abnormally increased tracer uptake in multiple nodal sites and organs, indicating the aggressiveness of the disease status, 18F-FAPI PET showed no obvious FAPI uptake in any of the FDG-avid lesions. Our case suggests that low expression of FAP in diffuse large B-cell lymphoma, as indicated by FAPI PET, might help determine a subgroup of patients with poorer outcome.
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