Abstract
A novel heterodyne Doppler interferometer method for compensating motion artifacts caused by cardiac motion in intracoronary optical frequency domain imaging (OFDI) is demonstrated. To track the relative motion of a catheter with regard to the vessel, a motion tracking system is incorporated with a standard OFDI system by using wavelength division multiplexing (WDM) techniques. Without affecting the imaging beam, dual WDM monochromatic beams are utilized for tracking the relative radial and longitudinal velocities of a catheter-based fiber probe. Our results demonstrate that tracking instantaneous velocity can be used to compensate for distortion in the images due to motion artifacts, thus leading to accurate reconstruction and volumetric measurements with catheter-based imaging.
Highlights
The integration of Fourier-domain detection strategies in optical coherence tomography has opened the possibility of high-resolution, cross-sectional imaging over large fields of view in biological tissues [1,2,3,4]
Optical frequency domain imaging (OFDI), which is based on frequency domain ranging techniques, has been applied through narrow diameter catheters and endoscopes [5] for imaging the coronary arteries [6,7,8,9] and distal esophagus [10] in patients
We demonstrate a novel motion tracking system using a heterodyne Doppler interferometer to compensate for image distortion in intracoronary OFDI
Summary
The integration of Fourier-domain detection strategies in optical coherence tomography has opened the possibility of high-resolution, cross-sectional imaging over large fields of view in biological tissues [1,2,3,4]. In intracoronary OFDI, a chirped beam probes the radial profile of the vessel being imaged. The motor controls the velocity of the fiber probe relative to its protective sheath, the sheath itself can move significantly within the coronary artery during the cardiac cycle, resulting in image distortion (Fig. 2). We demonstrate a novel motion tracking system using a heterodyne Doppler interferometer to compensate for image distortion in intracoronary OFDI. This method uses dual, wavelength division multiplexed (WDM) monochromatic beams to track the relative radial and longitudinal vessel motion. The re-registration of scans is performed with the Doppler frequency information, showing the improvement in endoscopic images
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