Compatible stability of reduning injection with solvents

Abstract

To investigate the compatible stability of Reduning injection in different dosages with 5% glucose injection and 0.9% sodium chloride injection. The changes before and after compatible application of Reduning injection with 5% glucose injection and 0.9% sodium chloride injection (5: 250, 10: 250, 20: 250, 30: 250, 40: 250, 50: 250, 62. 5: 250) on color, clarity, pH, main ingredients and atlas of HPLC were determined. There were no difference in the color, clarity, pH, the main ingredients and liquid fingerprints of the mixture solutions, but the insoluble particles in them showed significant difference within 6 h. Reduning injection is compatible in different concentrations with 5% glucose injection or 0.9% sodium chloride injection within 4 h, in clinic, it should be used within 2 h, the volume of Reduning injection with 5% glucose injection or 0.9% sodium chloride injection should be no more than 50 mL.