Abstract
Many clinicians use the linear-quadratic (LQ) model in estimating doses of stereotactic radiation therapy, because there is no other adequate dose-conversion model. The LQ model is, however, considered unreliable in converting hypofractionated doses to single doses. The purpose of this study was to evaluate the applicability of the repairable conditionally-repairable (RCR) model [S = exp(-aD) + bDexp(-cD)] and the multi-target (MT) model {S = exp(-D/d1)[1-(1-exp(-D/d0))n]} to high-dose-per-fraction radiation therapy in comparison with the LQ model.
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