Comparison Study of the Two Biometers Based on Swept-Source Optical Coherence Tomography Technology.

Jing Dong,Jinhan Yao,Shuimiao Chang,Xiaogang Wang,Piotr Kanclerz,Ramin Khoramnia

doi:10.3390/diagnostics12030598

Abstract

This research aimed to investigate the potential differences in the parameters, including axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), flat keratometry (Kf), steep keratometry (Ks), mean keratometry (Km), astigmatism, white-to-white (WTW) distance, acquired rate, and intraocular lens (IOL) power, between the two swept-source optical coherence tomography (SS-OCT) biometers, the ANTERION (biometer A) and IOLMaster 700 (biometer B). In a prospective observational comparative case series study, we enrolled 198 eyes undergoing cataract surgery. The AL, CCT, ACD, LT, Kf, Ks, Km, astigmatism, WTW, acquired rate, and IOL power were assessed. McNemar tests compared the acquired rate, and the paired sample t-test compared the quantitative measurement results between the groups. Nineteen eyes were excluded owing to missing AL data for either biometer. Finally, data from 179 eyes were analyzed. Between the two devices, no significant difference was found in AL, astigmatism magnitude, J0, and J45, while significant differences existed in CCT, ACD, LT, Kf, Ks, Km, WTW, astigmatism axis, and IOL power; no statistical significance was found in the AL acquired rate (biometer A, 90.9% and biometer B, 93.9%). Approximately 65.4% of eyes demonstrated ≥0.5-D difference in IOL power between the two biometers. In conclusion, the two biometers showed significant differences in all measurements (CCT, ACD, LT, K, WTW, astigmatism axis, and IOL power), except for AL.

Highlights

With the development of refractive cataract surgery and premium intraocular lenses (IOL), precise and accurate biometric measurements play an important role in IOL calculations
A recent study from Panthier et al [7] demonstrated that the two biometers (ANTERION and IOLMaster 700) provided good repeatability and high correlation for the anterior parameter measurements, such as axial length (AL), mean keratometry (Km), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), and white-to-white (WTW) distance, and all these parameters were not interchangeable
We found significant differences in the Ks, Kf, and Km measurements between the two devices [7,8,14]

Summary

Introduction

With the development of refractive cataract surgery and premium intraocular lenses (IOL), precise and accurate biometric measurements play an important role in IOL calculations. Different from ANTERION, IOLMaster 700 (i.e., biometer B; Carl Zeiss Meditec AG, Jena, Germany) SS-OCT biometry uses a 1060-nm wavelength as the light source, which is a shorter wavelength than that of ANTERION. It can measure the biometric data and provide a cross-sectional image of a small central macular area to testify the patient’s fixation during data capture [6]. A recent study from Panthier et al [7] demonstrated that the two biometers (ANTERION and IOLMaster 700) provided good repeatability and high correlation for the anterior parameter measurements, such as AL, mean keratometry (Km), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), and white-to-white (WTW) distance, and all these parameters were not interchangeable. As a supplement to the abovementioned study, this study aimed to determine the correlation, consistency, and level of agreement of other ocular parameters between the two biometers

Objectives

Methods

Results