Abstract

PurposeTo investigate the effect of pupil dilation on ocular biometric parameters and intraocular lens (IOL) power calculation in schoolchildren using the Lenstar LS 900.MethodsOne hundred forty eyes of 140 healthy schoolchildren were included in the analysis. Axial length (AL), central corneal thickness (CCT), aqueous depth (AD), anterior chamber depth (ACD), lens thickness (LT), flat keratometry (K), steep K, astigmatism, white-to-white (WTW), and iris/pupil barycenter distance were measured, before and after pupil dilation. Anterior segment length (ASL) was defined as the sum of ACD and LT, and lens position (LP) was defined as ACD plus half of the LT. The relative lens position (RLP) was defined as LP divided by AL. IOL power was calculated using the eight formulas (Hill-RBF, Barrett, Haigis, Hoffer Q, Holladay, Olsen, SRK II, and SRK/T) integrated in the Lenstar LS 900. Parameters before and after pupil dilation were compared.ResultsAL, AD, ACD, LT, ASL, LP, RLP, flat K, iris barycenter distance, pupil barycenter distance, and PD differed significantly after pupil dilation (P < 0.001 in all cases), as compared to before dilation. The Olsen formula demonstrated significant differences in the magnitude of astigmatism (P = 0.010) and IOL power (P = 0.003) after pupil dilation. Using the different formulas, 23.6–40.7% of participants had IOL power changes of more than 0.50 diopters, while 0.7–1.4% had IOL changes of more than 1.0 diopter after pupil dilation.ConclusionsDilated and undilated pupil size affected the Lenstar LS 900 measurement of some ocular biometric parameters, and pupil dilation led to IOL power changes exceeding 0.50 diopters with a high percentage (from 23.6% to 40.7%) in schoolchildren, which should be noticed in clinical practice.

Highlights

  • Since its introduction in 1999 with the development of IOLMasterTM, non-invasive optical biometry has increasingly been used by clinicians to determine ocular parameters and intraocular lens (IOL) power [1]

  • Dilated and undilated pupil size affected the Lenstar LS 900 measurement of some ocular biometric parameters, and pupil dilation led to IOL power changes exceeding 0.50 diopters

  • Effect of pupil dilation on biometry and IOL power calculation with a high percentage in schoolchildren, which should be noticed in clinical practice

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Summary

Introduction

Since its introduction in 1999 with the development of IOLMasterTM, non-invasive optical biometry has increasingly been used by clinicians to determine ocular parameters and intraocular lens (IOL) power [1]. The latest Lenstar software (version 2.5.2) includes three new formulas (Hill-RBF, Barrett, and Olsen formulas), in addition to the five standard integrated formulas (Haigis, Hoffer Q, Holladay, SRK II, and SRK/T), providing cataract surgeons with more precise target refraction values. Several studies have investigated the influence of pupil dilation or cycloplegia on biometric parameters (AL, ACD, and keratometric values) and IOL power calculation (using the SRK/T, Holladay 1, Hoffer Q, Haigis formula) by the Lenstar LS 900 or IOLMaster [4,5,6,7,8]

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