Abstract

Objective To investigate the therapeutic effect of esomeprazole and omeprazole in the combined treatment with rebamipide for peptic ulcer. Methods A total of 112 patients with peptic ulcer patients admitted to Yanhu District People’s Hospital of Yuncheng from January 2016 to May 2018 were selected. And they were divided into two groups by random number table method, with 56 cases in each group. Patients in control group were treated with esomeprazole combined with rebamipide, while patients in observation group were treated with omeprazole combined with rebamipide. The quality of ulcer healing, adverse reactions, Helicobacter pylori (Hp) eradication rate and clinical treatment effect were compared between the two groups. Results After treatment, the scores of quality factors of ulcer healing were decreased in the two groups, and the differences were statistically significant (P 0.05). The incidence of adverse reactions, eradication rate of Hp and total effective rate of clinical treatment in obervation group did not significantly differ from those in control group (P>0.05). Conclusions Esomeprazole and omeprazole in combination with rebamipide both play important roles in the treatment of peptic ulcer. Clinicians should formulate protocol of drug according to actual condition. Key words: Peptic ulcer; Ribbapet; Aprazole; Quality of ulcer healing; Adverse reactions

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.